KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF2A
All Species:
29.7
Human Site:
Y654
Identified Species:
72.59
UniProt:
O00139
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00139
NP_001091981.1
706
79955
Y654
E
M
T
E
E
V
D
Y
D
V
D
S
Y
A
T
Chimpanzee
Pan troglodytes
XP_513133
684
76927
E636
E
Q
P
D
Y
D
L
E
T
F
V
N
K
A
E
Rhesus Macaque
Macaca mulatta
XP_001085185
922
103117
Y870
E
M
T
E
E
V
D
Y
D
V
D
S
Y
A
T
Dog
Lupus familis
XP_535249
706
79925
Y654
E
M
T
E
E
V
D
Y
D
V
D
S
Y
A
T
Cat
Felis silvestris
Mouse
Mus musculus
P28740
705
79738
Y653
E
M
T
E
E
V
D
Y
D
V
D
S
Y
A
T
Rat
Rattus norvegicus
Q9WV63
705
79774
Y653
E
M
T
E
E
V
D
Y
D
V
D
S
Y
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506273
959
105390
P838
C
S
S
G
P
I
L
P
L
L
H
P
S
S
I
Chicken
Gallus gallus
Q5ZKV8
706
79845
Y654
E
M
T
E
E
V
D
Y
D
V
D
S
Y
A
T
Frog
Xenopus laevis
Q91637
682
77396
Y630
E
M
T
E
E
V
D
Y
D
A
D
S
Y
A
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960Z0
805
88653
Y754
N
L
T
N
Y
V
D
Y
D
Q
D
S
Y
C
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.9
76.2
99.2
N.A.
98
98.5
N.A.
59.8
95.1
84.6
N.A.
N.A.
47.8
N.A.
N.A.
N.A.
Protein Similarity:
100
74.2
76.3
99.2
N.A.
99.1
99.2
N.A.
65.4
97.8
88.5
N.A.
N.A.
64.2
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
0
100
93.3
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
26.6
100
93.3
N.A.
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
80
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
10
0
10
80
0
80
0
80
0
0
0
0
% D
% Glu:
80
0
0
70
70
0
0
10
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% K
% Leu:
0
10
0
0
0
0
20
0
10
10
0
0
0
0
0
% L
% Met:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
10
0
10
0
0
10
0
0
0
10
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
0
0
0
0
0
0
0
80
10
10
0
% S
% Thr:
0
0
80
0
0
0
0
0
10
0
0
0
0
0
70
% T
% Val:
0
0
0
0
0
80
0
0
0
60
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
20
0
0
80
0
0
0
0
80
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _